Jan 12, 2026

Featuring an interview with Dr Scott Kopetz, including the following topics: 

• Circulating tumor DNA (ctDNA)-guided adjuvant chemotherapy de-escalation in the treatment of Stage III colon cancer from the ctDNA-negative cohort of the DYNAMIC-III trial (0:00)
• Prognostic and predictive role of ctDNA in the management of...

Jan 6, 2026

Featuring an interview with Dr Scott Kopetz, including the following topics:

• Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) and survival among patients with resectable colorectal cancer (CRC) in the CIRCULATE-Japan GALAXY trial (0:00)
• ctDNA for detection of MRD in patients with CRC in the...

Dec 22, 2025

Featuring perspectives from Dr Yelena Y Janjigian, including the following topics:

• Introduction (0:00)
• Case: A man in his early 60s with a history of Barrett's esophagus presents with HER2-positive metastatic esophageal adenocarcinoma and a PD-L1 combined positive score (CPS) of 3 — Jennifer Yannucci, MD (10:20)

Dec 13, 2025

Featuring perspectives from Dr Manish A Shah, moderated by Dr Stephen “Fred” Divers, including the following topics: 

• Highlights and Principles of Management of Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma — Dr Shah (0:00)
• Case: A man in his early 50s with microsatellite instability-high...

Nov 21, 2025

Featuring perspectives from Dr Tanios Bekaii-Saab and Dr Kristen K Ciombor, including the following topics:

• Introduction: Assessment of HER2 Status (0:00)
• Case: An otherwise healthy woman in her early 50s with HER2-positive metastatic gallbladder cancer and multiple intrahepatic metastases — Jeremy Lorber, MD (7:33)