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  2. Genitourinary Cancers — 5-Minute Journal Club Issue 2 with Professor Thomas Powles: Current and Future Role of Tumor-Informed Circulating Tumor DNA Assays

Genitourinary Cancers — 5-Minute Journal Club Issue 2 with Professor Thomas Powles: Current and Future Role of Tumor-Informed Circulating Tumor DNA Assays

Jun 5, 2026

Featuring perspectives from Prof Thomas Powles, including the following topics:

  • Circulating tumor DNA (ctDNA) analyses with adjuvant nivolumab for MIBC in the CheckMate 274 study (0:00)
  • Use of ctDNA to guide response-adapted bladder preservation for patients with MIBC (2:27)
  • ctDNA response-adapted treatment de-escalation for patients with metastatic urothelial carcinoma: The CT-READ trial (10:26)
  • Emerging data and studies regarding urinary tumor DNA (18:04)

CME information and select publications