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Apr 7, 2026

Featuring an interview with Dr Ravin Ratan, including the following topics:

  • Case: A woman in her early 40s who develops intense nausea and vomiting and is diagnosed with a pelvic desmoid tumor elects surveillance and experiences spontaneous regression of the tumor (0:00)
  • Case: A woman in her late 30s with a painful...


Mar 16, 2026

Featuring an interview with Dr Ravin Ratan, including the following topics:

  • Efficacy and safety of long-term continuous nirogacestat treatment in adults with desmoid tumors: Results from the Phase III DeFi trial (0:00)
  • Onset and resolution of ovarian toxicity with nirogacestat treatment for desmoid tumors: Updated...


Jun 24, 2025

Featuring an interview with Dr Patrick Y Wen, including the following topics:

  • Glioma classification (0:00)
  • Efficacy and safety of vorasidenib in the management of IDH-mutant gliomas (4:50)
  • Case: A woman in her early 30s with a Grade 2 astrocytoma and an IDH R132H mutation and residual disease...


Jun 23, 2025

Featuring a slide presentation and related discussion from Dr Patrick Y Wen, including the following topics:

  • Classification and pathologic diagnosis of gliomas (0:00)
  • Role of IDH inhibitors in the management of low-grade gliomas (6:37)
  • Ongoing trials and remaining questions in the management of IDH-mutant gliomas...


Oct 18, 2024

Featuring perspectives from Dr Thierry Alcindor and Dr Mrinal Gounder, including the following topics:

  • Introduction: Biology and Clinical Presentation (0:00)
  • Case: A man in his mid 60s with desmoid fibromatosis — Dr Alcindor (12:36)
  • Tyrosine Kinase Inhibitors (24:51)
  • Gamma Secretase Inhibitors (31:02)
  • Case: A woman...