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Oct 25, 2022

Featuring a slide presentation and related discussion from Dr Justin Gainor, including the following topics:

  • Biology of RET Genetic Alterations in Cancer (0:00)
  • Early Efforts to Target RET Alterations in Non-Small Cell Lung Cancer (NSCLC) (1:44)
  • Mechanisms of Action of Selective RET Inhibitors (3:58)
  • Clinical Trial Evidence Supporting Selpercatinib Therapy for RET-Altered NSCLC (5:04)
  • Updated Efficacy and Safety Results with Pralsetinib Therapy for RET-Altered NSCLC (13:14)
  • Mechanisms of Resistance to Selective RET Inhibitors (19:33)

CME information and select publications