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Aug 31, 2023

Featuring perspectives from Dr Michael Wang, including the following topics:

  • Algorithm for observation versus initiation of therapy for newly diagnosed mantle cell lymphoma (MCL) (0:00)
  • First- and second-line therapy approaches for MCL (7:26)
  • Case: A 45-year-old woman with relapsed MCL receiving acalabrutinib who develops severe headaches (10:21)
  • Current role of ibrutinib in the treatment of MCL; use of single-agent venetoclax and of zanubrutinib in the treatment algorithm (14:59)
  • Case: A 68-year-old man presenting with an enlarged spleen, no lymphadenopathy and a white blood cell count of 300,000 is diagnosed with MCL (17:48)
  • Case: A 71-year-old man with multiregimen-relapsed, nodular type MCL presents with lymphadenopathy and a 3-cm tumor near the mediastinum (22:38)
  • Patient selection for chimeric antigen receptor T-cell therapy (25:59)
  • Novel and investigational therapeutic approaches for MCL (30:11)
  • Treatment approaches for other histological variants of MCL (39:00)

CME information and select publications