Research To Practice | Oncology Videos: HR-Positive Metastatic Breast Cancer — An Interview with Dr Seth Wander on Biomarker Assessment and Related Treatment Decision-Making (Companion Faculty Lecture)

HR-Positive Metastatic Breast Cancer — An Interview with Dr Seth Wander on Biomarker Assessment and Related Treatment Decision-Making (Companion Faculty Lecture)

Apr 16, 2026

Featuring a slide presentation and related discussion from Dr Seth Wander, including the following topics:

Biological impact of clinically relevant biomarkers (eg, ESR1 mutations, PIK3CA/AKT1/PTEN alterations) (0:00)
Methodologies for biomarker assessment in clinical practice: Tissue versus liquid biopsy (5:21)
Methodologies for biomarker assessment in clinical practice: Novel platforms (13:56)
Appropriate timing for assessment of ESR1 and PI3K pathway alterations (17:34)
Evolving guidelines for routine biomarker evaluation (21:37)
Implications of precision oncology clinical trials for future biomarker utility (25:07)
Summary, key questions, future directions (33:09)