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Aug 7, 2020

Proceedings from the fourth in a series of 11 integrated webinars held in association with the 2020 ONS Annual Congress. Featuring perspectives from Ms Amy Goodrich, Dr Brad S Kahl, Ms Robin Klebig and Dr Jeff Sharman.

  • Introduction (00:00)
  • Clinical presentation of chronic lymphocytic leukemia (CLL) and biomarkers predictive of response (4:58)
  • Differences in clinical manifestation between CLL and small lymphocytic lymphoma; educating the asymptomatic patient about the benefits of watching and waiting (12:49)
  • Counseling patients with CLL about the risks and benefits of acalabrutinib/obinutuzumab (18:47)
  • Mechanism of action, side effects and optimal integration of novel BTK and Bcl-2 inhibitors for CLL (26:22)
  • Caring for patients on ibrutinib therapy; role of the oncology nurse in providing emotional and psychological support (36:56)
  • Communicating the significance of clinical trial participation to patients with CLL; results from the Phase III CLL14 trial assessing fixed-duration venetoclax/obinutuzumab as up-front therapy (46:17)
  • Optimal use of venetoclax for CLL; patient education about, monitoring for and management of tumor lysis syndrome (54:53)
  • Selection and duration of front-line therapy for patients with CLL (1:03:41)
  • Monitoring patients receiving venetoclax to prevent tumor lysis syndrome (1:15:07)
  • Emerging data with the use of BTK inhibitor therapy for patients with COVID-19 (1:19:45)

CNE information and select publications