Dec 5, 2024

Featuring perspectives from Dr Priyanka Sharma and Dr Sara M Tolaney, including the following topics:

• Introduction: Metastatic Triple-Negative Breast Cancer (mTNBC) — The Patient Perspective (0:00)
• Selection and Sequencing of Antibody-Drug Conjugates (5:09)
• Dosing and Tolerability of Sacituzumab Govitecan; Use of Anthracyclines (14:39)
• Case: A woman in her early 60s with relapsed TNBC (HER2 2+) who experiences disease progression on T-DXd (Grade 2 interstitial lung disease) and receives sacituzumab govitecan — Shaachi Gupta, MD, MPH (22:04)
• Discussing Palliative and End-of-Life Care (32:40)
• PARP Inhibitors for TNBC with Somatic versus Germline Mutations; Cytopenias with PARP Inhibitors (37:53)
• The “Art of Oncology” — Building Trust with Patients and Family Members (45:05)
• Case: A woman in her mid 60s with recurrent TNBC with extensive chest wall involvement — Dr Gupta (48:44)
• Case: A man in his mid 40s with multiregimen-refractory AR-positive TNBC with an ERBB2 exon 20 insertion mutation — Dr Gupta (52:53)

CME information and select publications